one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity related to bortezomib, a proteasome inhibitor used in the treatment of numerous myeloma. Its synthesis or research is essential for making certain the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug Employed in the procedure of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-one): A vital compound from the synthesis of imatinib, a drug that targets certain kinds of most cancers, like Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their examine is vital for optimizing the generation procedure and guaranteeing higher purity.
Lapatinib Intermediate (CAS 4-[2-(2-Amino-4 NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Numerous intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers for example ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment method of colorectal most cancers and small mobile lung 2 most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, together with antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to control blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are used in food, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication utilized to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).